CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.140 | Metal-dependent hydrolases |
Domain Context
CATH Clusters
| Superfamily | Metal-dependent hydrolases |
| Functional Family | Dihydroorotase |
Enzyme Information
| 3.5.2.3 |
Dihydroorotase.
based on mapping to UniProt P05020
(S)-dihydroorotate + H(2)O = N-carbamoyl-L-aspartate.
|
UniProtKB Entries (1)
| P05020 |
PYRC_ECOLI
Escherichia coli K-12
Dihydroorotase
|
PDB Structure
| PDB | 2E25 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of the T109S mutant of Escherichia coli dihydroorotase complexed with the inhibitor 5-fluoroorotate: catalytic activity is reflected by the crystal form
Acta Crystallogr.,Sect.F
|
