CATH Domain 2dtrA02

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.60	Diphtheria Toxin Repressor; domain 2
	1.10.60.10	Iron dependent repressor, metal binding and dimerisation domain

Domain Context

CATH Clusters

Superfamily	Iron dependent repressor, metal binding and dimerisation domain
Functional Family	Iron dependent repressor

Enzyme Information

UniProtKB Entries (1)

DTXR_CORDI

Corynebacterium diphtheriae NCTC 13129

Diphtheria toxin repressor

PDB Structure

PDB	2DTR
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	High-resolution structure of the diphtheria toxin repressor complexed with cobalt and manganese reveals an SH3-like third domain and suggests a possible role of phosphate as co-corepressor. Qiu, X., Pohl, E., Holmes, R.K., Hol, W.G. Biochemistry