CATH Domain 2dp3A00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.20	Alpha-Beta Barrel
	3.20.20	TIM Barrel
	3.20.20.70	Aldolase class I

Domain Context

CATH Clusters

Superfamily	Aldolase class I
Functional Family	Triosephosphate isomerase

Enzyme Information

4.2.3.3	Methylglyoxal synthase. based on mapping to UniProt P36186 Glycerone phosphate = methylglyoxal + phosphate. -!- Does not act on D-glyceraldehyde 3-phosphate. -!- Formerly EC 4.2.99.11.
5.3.1.1	Triose-phosphate isomerase. based on mapping to UniProt P36186 D-glyceraldehyde 3-phosphate = glycerone phosphate.

UniProtKB Entries (1)

TPI1_GIAIN

Giardia intestinalis

Triosephosphate isomerase

PDB Structure

PDB	2DP3
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Disulfide Bridges in the Mesophilic Triosephosphate Isomerase from Giardia lamblia Are Related to Oligomerization and Activity Reyes-Vivas, H., Diaz, A., Peon, J., Mendoza-Hernandez, G., Hernandez-Alcantara, G., De la Mora-De la Mora, I., Enriquez-Flores, S., Dominguez-Ramirez, L., Lopez-Velazquez, G. J.Mol.Biol.