CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | Malate dehydrogenase |
Enzyme Information
| 1.1.1.299 |
Malate dehydrogenase (NAD(P)(+)).
based on mapping to UniProt Q9YEA1
(S)-malate + NAD(P)(+) = oxaloacetate + NAD(P)H.
-!- This enzyme, which was characterized from the methanogenic archaeon Methanobacterium thermoautotrophicum, catalyzes only the reduction of oxaloacetate, and can use NAD(+) and NADP(+) with similar specific activity. -!- Different from EC 1.1.1.37, EC 1.1.1.82 and EC 1.1.5.4.
|
UniProtKB Entries (1)
| Q9YEA1 |
MDH_AERPE
Aeropyrum pernix K1
Malate dehydrogenase
|
PDB Structure
| PDB | |
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| Primary Citation |
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