CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.1740 | Rna Polymerase Sigma Factor; Chain: A |
|
1.10.1740.100 | Set2, Rpb1 interacting domain |
Domain Context
CATH Clusters
| Superfamily | Set2, Rpb1 interacting domain |
| Functional Family | Histone-lysine N-methyltransferase |
Enzyme Information
| 2.1.1.43 |
Histone-lysine N-methyltransferase.
based on mapping to UniProt P46995
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
|
UniProtKB Entries (1)
| P46995 |
SET2_YEAST
Saccharomyces cerevisiae S288C
Histone-lysine N-methyltransferase, H3 lysine-36 specific
|
PDB Structure
| PDB | 2C5Z |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Structure and carboxyl-terminal domain (CTD) binding of the Set2 SRI domain that couples histone H3 Lys36 methylation to transcription.
J. Biol. Chem.
|
