CATH Domain 2c5lA00

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	KRAS proto-oncogene, GTPase

Enzyme Information

UniProtKB Entries (1)

PLCE1_HUMAN

Homo sapiens

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1

PDB Structure

PDB	2C5L
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural and Mechanistic Insights Into Ras Association Domains of Phospholipase C Epsilon Bunney, T.D., Harris, R., Gandarillas, N.L., Josephs, M.B., Roe, S.M., Sorli, S.C., Paterson, H.F., Rodrigues-Lima, F., Esposito, D., Ponting, C.P., Gieschik, P., Pearl, L.H., Driscoll, P.C., Katan, M. Mol.Cell