CATH Domain 2a4hA01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.30	Glutaredoxin
	3.40.30.50	Sep15/SelM thioredoxin-like domain, active-site redox motif

Domain Context

CATH Clusters

Superfamily	Sep15/SelM thioredoxin-like domain, active-site redox motif
Functional Family	15 kDa selenoprotein

Enzyme Information

UniProtKB Entries (1)

Q9VVJ7_DROME

Drosophila melanogaster

CG7484 protein

PDB Structure

PDB	2A4H
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Escherichia
Primary Citation	NMR Structures of the Selenoproteins Sep15 and SelM Reveal Redox Activity of a New Thioredoxin-like Family. Ferguson, A.D., Labunskyy, V.M., Fomenko, D.E., Chelliah, Y., Amezcua, C.A., Rizo, J., Gladyshev, V.N., Deisenhofer, J. J.Biol.Chem.