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1 keywords

CATH Domain 1yxdB00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.70 Aldolase class I

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family 4-hydroxy-tetrahydrodipicolinate synthase

Enzyme Information

4.3.3.7
4-hydroxy-tetrahydrodipicolinate synthase.
based on mapping to UniProt P0A6L2
Pyruvate + L-aspartate-4-semialdehyde = (4S)-4-hydroxy-2,3,4,5- tetrahydro-(2S)-dipicolinate + H(2)O.
-!- Formerly EC 4.2.1.52.

UniProtKB Entries (1)

P0A6L2
DAPA_ECOLI
Escherichia coli K-12
4-hydroxy-tetrahydrodipicolinate synthase

PDB Structure

PDB 1YXD
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance.
Dobson, R.C., Griffin, M.D., Jameson, G.B., Gerrard, J.A.
Acta Crystallogr.,Sect.D
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