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1 keywords

CATH Domain 1y5yB00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.230 Ribosomal Protein S5; domain 2
Homologous Superfamily 3.30.230.60 Formaldehyde-activating enzyme

Domain Context

CATH Clusters

Superfamily Formaldehyde-activating enzyme
Functional Family 5,6,7,8-tetrahydromethanopterin hydro-lyase

Enzyme Information

4.2.1.147
5,6,7,8-tetrahydromethanopterin hydro-lyase.
based on mapping to UniProt Q9FA38
5,6,7,8-tetrahydromethanopterin + formaldehyde = 5,10- methylenetetrahydromethanopterin + H(2)O.
-!- Found in methylotrophic bacteria and methanogenic archaea.

UniProtKB Entries (1)

Q9FA38
FAE_METEA
Methylorubrum extorquens AM1
5,6,7,8-tetrahydromethanopterin hydro-lyase

PDB Structure

PDB 1Y5Y
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
How an enzyme binds the C1-carrier tetrahydromethanopterin: Structure of the tetrahydromethanopterin dependent formaldehyde-activating enzyme (Fae) from Methylobacterium extorquens AM1
Acharya, P., Goenrich, M., Hagemeier, C.H., Demmer, U., Vorholt, J.A., Thauer, R.K., Ermler, U.
J.Biol.Chem.
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