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1 keywords

CATH Domain 1xqhA02

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.170 Beta Complex
Topology 2.170.270 Beta-clip-like
Homologous Superfamily 2.170.270.10 SET domain

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family Histone-lysine N-methyltransferase SETD7

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q8WTS6
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

P04637
P53_HUMAN
Homo sapiens
Cellular tumor antigen p53

PDB Structure

PDB 1XQH
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Regulation of p53 activity through lysine methylation
Chuikov, S., Kurash, J.K., Wilson, J.R., Xiao, B., Justin, N., Ivanov, G.S., McKinney, K., Tempst, P., Prives, C., Gamblin, S.J., Barlev, N.A., Reinberg, D.
Nature
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