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1 keywords

CATH Domain 1vprA02

CATH Classification

Level CATH Code Description
Class 4 Few Secondary Structures
Architecture 4.10 Irregular
Topology 4.10.1310 Dinoflagellate luciferase repeat
Homologous Superfamily 4.10.1310.10 Dinoflagellate luciferase repeat

Domain Context

CATH Clusters

Superfamily Dinoflagellate luciferase repeat
Functional Family

Enzyme Information

1.13.12.18
Dinoflagellate luciferase.
based on mapping to UniProt O77206
Dinoflagellate luciferin + O(2) = oxidized dinoflagellate luciferin + H(2)O + light.
-!- A luciferase from dinoflagelates such as Gonyaulax polyhedra, Lingulodinium polyedrum, Noctiluca scintillans, and Pyrocystis lunula. -!- It is a single protein with three luciferase domains. -!- The luciferin is strongly bound by a luciferin binding protein above a pH of 7.

UniProtKB Entries (1)

O77206
LUCIF_LINPO
Lingulodinium polyedra
Dinoflagellate luciferase

PDB Structure

PDB 1VPR
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of a pH-regulated luciferase catalyzing the bioluminescent oxidation of an open tetrapyrrole
Schultz, L.W., Liu, L., Cegielski, M., Hastings, J.W.
Proc.Natl.Acad.Sci.USA
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