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CATH Classification

Domain Context

CATH Clusters

Superfamily Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Functional Family 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

Enzyme Information

2.7.7.60
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase.
based on mapping to UniProt Q9X1B3
CTP + 2-C-methyl-D-erythritol 4-phosphate = diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol.
-!- ATP or UTP can replace CTP, but both are less effective. -!- GTP and TTP are not substrates. -!- Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis.

UniProtKB Entries (1)

Q9X1B3
ISPD_THEMA
Thermotoga maritima MSB8
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

PDB Structure

PDB 1VPA
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (TM1393) from Thermotoga maritima at 2.67 A resolution
Joint Center for Structural Genomics (JCSG)
To be published
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