CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1780 | QueA-like |
|
3.40.1780.10 | QueA-like |
Domain Context
CATH Clusters
| Superfamily | QueA-like |
| Functional Family | S-adenosylmethionine:tRNA ribosyltransferase-isomerase |
Enzyme Information
| 2.4.99.17 |
S-adenosylmethionine:tRNA ribosyltransferase-isomerase.
based on mapping to UniProt Q9WZ44
S-adenosyl-L-methionine + 7-aminomethyl-7-carbaguanosine(34) in tRNA = L-methionine + adenine + epoxyqueuosine(34) in tRNA.
-!- The reaction is a combined transfer and isomerization of the ribose moiety of S-adenosyl-L-methionine to the modified guanosine base in the wobble position in tRNAs specific for Tyr, His, Asp or Asn. -!- It is part of the queuosine biosynthesis pathway.
|
UniProtKB Entries (1)
| Q9WZ44 |
QUEA_THEMA
Thermotoga maritima MSB8
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
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PDB Structure
| PDB | |
| External Links | |
| Method | |
| Organism | |
| Primary Citation |
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