CATH Domain 1vgvD01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.2000	Glycogen Phosphorylase B;

Domain Context

CATH Clusters

Superfamily	Glycogen Phosphorylase B;
Functional Family	UDP-N-acetylglucosamine 2-epimerase

Enzyme Information

5.1.3.14

UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing).

based on mapping to UniProt P27828

UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-mannosamine.

-!- This bacterial enzyme catalyzes the reversible interconversion of UDP-GlcNAc and UDP-ManNAc. -!- The latter is used in a variety of bacterial polysaccharide biosyntheses. -!- Cf. EC 3.2.1.183.

UniProtKB Entries (1)

P27828

WECB_ECOLI

Escherichia coli K-12

UDP-N-acetylglucosamine 2-epimerase

PDB Structure

PDB	1VGV
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural analysis of a set of proteins resulting from a bacterial genomics project Badger, J., Sauder, J.M., Adams, J.M., Antonysamy, S., Bain, K., Bergseid, M.G., Buchanan, S.G., Buchanan, M.D., Batiyenko, Y., Christopher, J.A., Emtage, S., Eroshkina, A., Feil, I., Furlong, E.B., Gajiwala, K.S., Gao, X., He, D., Hendle, J., Huber, A., Hoda, K., Kearins, P., Kissinger, C., Laubert, B., Lewis, H.A., Lin, J., Loomis, K., Lorimer, D., Louie, G., Maletic, M., Marsh, C.D., Miller, I., Molinari, J., Muller-Dieckmann, H.J., Newman, J.M., Noland, B.W., Pagarigan, B., Park, F., Peat, T.S., Post, K.W., Radojicic, S., Ramos, A., Romero, R., Rutter, M.E., Sanderson, W.E., Schwinn, K.D., Tresser, J., Winhoven, J., Wright, T.A., Wu, L., Xu, J., Harris, T.J. Proteins

Network disruptions