CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.470 | D-amino Acid Aminotransferase; Chain A, domain 1 |
|
3.30.470.20 | ATP-grasp fold, B domain |
Domain Context
CATH Clusters
| Superfamily | ATP-grasp fold, B domain |
| Functional Family | Alpha-aminoadipate--LysW ligase LysX protein |
Enzyme Information
| 6.3.2.43 |
[Amino group carrier protein]--L-2-aminoadipate ligase.
based on mapping to UniProt Q5SH23
ATP + [amino group carrier protein]-C-terminal-L-glutamate + L-2- aminoadipate = ADP + phosphate + [amino group carrier protein]-C- terminal-gamma-(L-2-aminoadip-2-yl)-L-glutamate.
-!- The enzymes from the thermophilic bacterium Thermus thermophilus and the thermophilic archaea Sulfolobus acidocaldarius and Sulfolobus tokodaii protect the amino group of L-2-aminoadipate by conjugation to the carrier protein LysW. -!- This reaction is part of the lysine biosynthesis pathway in these organisms. -!- Formerly EC 6.3.2.n4.
|
UniProtKB Entries (1)
| Q5SH23 |
LYSX_THET8
Thermus thermophilus HB8
Alpha-aminoadipate--LysW ligase LysX
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PDB Structure
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| Primary Citation |
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