CATH Domain 1tph100

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.20	Alpha-Beta Barrel
	3.20.20	TIM Barrel
	3.20.20.70	Aldolase class I

Domain Context

CATH Clusters

Superfamily	Aldolase class I
Functional Family	Triosephosphate isomerase

Enzyme Information

4.2.3.3	Methylglyoxal synthase. based on mapping to UniProt P00940 Glycerone phosphate = methylglyoxal + phosphate. -!- Does not act on D-glyceraldehyde 3-phosphate. -!- Formerly EC 4.2.99.11.
5.3.1.1	Triose-phosphate isomerase. based on mapping to UniProt P00940 D-glyceraldehyde 3-phosphate = glycerone phosphate.

UniProtKB Entries (1)

TPIS_CHICK

Gallus gallus

Triosephosphate isomerase

PDB Structure

PDB	1TPH
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of recombinant chicken triosephosphate isomerase-phosphoglycolohydroxamate complex at 1.8-A resolution. Zhang, Z., Sugio, S., Komives, E.A., Liu, K.D., Knowles, J.R., Petsko, G.A., Ringe, D. Biochemistry