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1 keywords

CATH Domain 1tfxD00

CATH Classification

Level CATH Code Description
Class 4 Few Secondary Structures
Architecture 4.10 Irregular
Topology 4.10.410 Factor Xa Inhibitor
Homologous Superfamily 4.10.410.10 Pancreatic trypsin inhibitor Kunitz domain

Domain Context

CATH Clusters

Superfamily Pancreatic trypsin inhibitor Kunitz domain
Functional Family Tissue factor pathway inhibitor

Enzyme Information

UniProtKB Entries (2)

P10646
TFPI1_HUMAN
Homo sapiens
Tissue factor pathway inhibitor
P00761
TRYP_PIG
Sus scrofa
Trypsin

PDB Structure

PDB 1TFX
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The second Kunitz domain of human tissue factor pathway inhibitor: cloning, structure determination and interaction with factor Xa.
Burgering, M.J., Orbons, L.P., van der Doelen, A., Mulders, J., Theunissen, H.J., Grootenhuis, P.D., Bode, W., Huber, R., Stubbs, M.T.
J.Mol.Biol.
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