CATH Domain 1sj8A02

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.120	Four Helix Bundle (Hemerythrin (Met), subunit A)
	1.20.120.230	Alpha-catenin/vinculin-like

Domain Context

CATH Clusters

Superfamily	Alpha-catenin/vinculin-like
Functional Family	Talin 2

Enzyme Information

UniProtKB Entries (1)

TLN1_MOUSE

Mus musculus

Talin-1

PDB Structure

PDB	1SJ8
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle Papagrigoriou, E., Gingras, A.R., Barsukov, I.L., Bate, N., Fillingham, I.J., Patel, B., Frank, R., Ziegler, W.H., Roberts, G.C., Critchley, D.R., Emsley, J. EMBO J.