CATH Domain 1sghA01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.20	Ubiquitin-like (UB roll)
	3.10.20.90	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Domain Context

CATH Clusters

Superfamily	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Functional Family	radixin isoform X1

Enzyme Information

UniProtKB Entries (1)

NHRF1_HUMAN

Homo sapiens

Na(+)/H(+) exchange regulatory cofactor NHE-RF1

PDB Structure

PDB	1SGH
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	The EBP50-moesin interaction involves a binding site regulated by direct masking on the FERM domain Finnerty, C.M., Chambers, D., Ingraffea, J., Faber, H.R., Karplus, P.A., Bretscher, A. J.Cell.Sci.