CATH Domain 1rxwA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.150	DNA polymerase; domain 1
	1.10.150.20	5' to 3' exonuclease, C-terminal subdomain

Domain Context

CATH Clusters

Superfamily	5' to 3' exonuclease, C-terminal subdomain
Functional Family	Flap endonuclease 1

Enzyme Information

3.1.-.-

Acting on ester bonds.

based on mapping to UniProt O29975

UniProtKB Entries (1)

FEN_ARCFU

Archaeoglobus fulgidus DSM 4304

Flap endonuclease 1

PDB Structure

PDB	1RXW
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair Chapados, B.R., Hosfield, D.J., Han, S., Qiu, J., Yelent, B., Shen, B., Tainer, J.A. Cell(Cambridge,Mass.)