×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

1 keywords

CATH Domain 1rqqD00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.505 SHC Adaptor Protein
Homologous Superfamily 3.30.505.10 SH2 domain

Domain Context

CATH Clusters

Superfamily SH2 domain
Functional Family

Enzyme Information

UniProtKB Entries (2)

P06213
INSR_HUMAN
Homo sapiens
Insulin receptor
Q9Z200
SH2B2_RAT
Rattus norvegicus
SH2B adapter protein 2

PDB Structure

PDB 1RQQ
External Links
Method X-RAY DIFFRACTION
Organism Spodoptera
Primary Citation
Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor.
Hu, J., Liu, J., Ghirlando, R., Saltiel, A.R., Hubbard, S.R.
Mol.Cell
CATH-Gene3D is a Global Biodata Core Resource Learn more...