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1 keywords

CATH Domain 1qxsD02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.360 Dihydrodipicolinate Reductase; domain 2
Homologous Superfamily 3.30.360.10 Dihydrodipicolinate Reductase; domain 2

Domain Context

CATH Clusters

Superfamily Dihydrodipicolinate Reductase; domain 2
Functional Family Glyceraldehyde-3-phosphate dehydrogenase

Enzyme Information

1.2.1.12
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).
based on mapping to UniProt P22513
D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH.
-!- Also acts very slowly on D-glyceraldehyde and some other aldehydes. -!- Thiols can replace phosphate.

UniProtKB Entries (1)

P22513
G3PG_TRYCR
Trypanosoma cruzi
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal

PDB Structure

PDB 1QXS
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase complexed with an analogue of 1,3-bisphospho-d-glyceric acid.
Ladame, S., Castilho, M.S., Silva, C.H., Denier, C., Hannaert, V., Perie, J., Oliva, G., Willson, M.
Eur.J.Biochem.
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