CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.140 | Cytidine Deaminase; domain 2 |
|
3.40.140.10 | Cytidine Deaminase, domain 2 |
Domain Context
CATH Clusters
| Superfamily | Cytidine Deaminase, domain 2 |
| Functional Family | Cytosine deaminase |
Enzyme Information
| 3.5.4.1 |
Cytosine deaminase.
based on mapping to UniProt Q12178
Cytosine + H(2)O = uracil + NH(3).
-!- Also acts on 5-methylcytosine.
|
UniProtKB Entries (1)
| Q12178 |
FCY1_YEAST
Saccharomyces cerevisiae S288C
Cytosine deaminase
|
PDB Structure
| PDB | 1P6O |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The 1.14 a crystal structure of yeast Cytosine deaminase. Evolution of nucleotide salvage enzymes and implications for genetic chemotherapy.
Structure
|
