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CATH Classification

Domain Context

CATH Clusters

Superfamily Rel homology domain (RHD), DNA-binding domain
Functional Family Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

Enzyme Information

UniProtKB Entries (1)

O95644
NFAC1_HUMAN
Homo sapiens
Nuclear factor of activated T-cells, cytoplasmic 1

PDB Structure

PDB 1NFA
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Unusual Rel-like architecture in the DNA-binding domain of the transcription factor NFATc.
Wolfe, S.A., Zhou, P., Dotsch, V., Chen, L., You, A., Ho, S.N., Crabtree, G.R., Wagner, G., Verdine, G.L.
Nature
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