CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.100 | NADP-dependent oxidoreductase domain |
Domain Context
CATH Clusters
| Superfamily | NADP-dependent oxidoreductase domain |
| Functional Family | 2,5-diketo-D-gluconic acid reductase A |
Enzyme Information
| 1.1.1.274 |
2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming).
based on mapping to UniProt Q46857
2-dehydro-D-gluconate + NADP(+) = 2,5-didehydro-D-gluconate + NADPH.
-!- The enzyme is involved in the catabolism of 2,5-didehydrogluconate. -!- cf. EC 1.1.1.346.
|
UniProtKB Entries (1)
| Q46857 |
DKGA_ECOLI
Escherichia coli K-12
2,5-diketo-D-gluconic acid reductase A
|
PDB Structure
| PDB | 1MZR |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of Escherichia coli DkgA, a broad-specificity aldo-keto reductase.
Proteins
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