CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1820 | alpha/beta hydrolase |
Domain Context
CATH Clusters
| Superfamily | alpha/beta hydrolase |
| Functional Family |
Enzyme Information
| 3.1.1.3 |
Triacylglycerol lipase.
based on mapping to UniProt P16233
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
-!- The pancreatic enzyme acts only on an ester-water interface; the outer ester links are preferentially hydrolyzed.
|
UniProtKB Entries (2)
| P02703 |
COL_PIG
Sus scrofa
Colipase
|
| P16233 |
LIPP_HUMAN
Homo sapiens
Pancreatic triacylglycerol lipase
|
PDB Structure
| PDB | 1LPA |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Interfacial activation of the lipase-procolipase complex by mixed micelles revealed by X-ray crystallography.
Nature
|
