CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Vitamin B12 import ATP-binding protein BtuD |
Enzyme Information
| 7.6.2.8 |
ABC-type vitamin B12 transporter.
based on mapping to UniProt P06611
ATP + H(2)O + vitamin B12-[cobalamin-binding protein](Side 1) = ADP + phosphate + vitamin B12(Side 2) + [cobalamin-binding protein](Side 1).
-!- An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. -!- Does not undergo phosphorylation during the transport process. -!- A bacterial enzyme that interacts with an extracytoplasmic substrate binding protein and mediates the high affinity uptake of cobalamin derivatives. -!- Formerly EC 3.6.3.33.
|
UniProtKB Entries (1)
| P06609 |
BTUC_ECOLI
Escherichia coli K-12
Vitamin B12 import system permease protein BtuC
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PDB Structure
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| Primary Citation |
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