CATH Domain 1kecB02

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.120	Penicillin G acylase, beta-roll domain
	2.30.120.10	Aminohydrolase, N-terminal nucleophile (Ntn) domain, beta-sheet knob region

Domain Context

CATH Clusters

Superfamily	2.30.120.10
Functional Family

Enzyme Information

3.5.1.11

Penicillin amidase.

based on mapping to UniProt P06875

Penicillin + H(2)O = a carboxylate + 6-aminopenicillanate.

UniProtKB Entries (1)

PAC_ECOLX

Escherichia coli

Penicillin G acylase

PDB Structure

PDB	1KEC
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural and kinetic studies on ligand binding in wild-type and active-site mutants of penicillin acylase. Alkema, W.B.L., Hensgens, C.M.H., Snijder, H.J., Keizer, E., Dijkstra, B.W., Janssen, D.B. Protein Eng.Des.Sel.