CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.980 | Molybdenum Cofactor Biosythetic Enzyme; Chain A |
|
3.40.980.10 | MoaB/Mog-like domain |
Domain Context
CATH Clusters
| Superfamily | MoaB/Mog-like domain |
| Functional Family | Molybdopterin molybdenumtransferase |
Enzyme Information
| 2.10.1.1 |
Molybdopterin molybdotransferase.
based on mapping to UniProt Q9NQX3
Adenylyl-molybdopterin + molybdate = molybdenum cofactor + AMP.
-!- Catalyzes the insertion of molybdenum into the ene-dithiol group of molybdopterin. -!- In eukaryotes this reaction is catalyzed by the N-terminal domain of a fusion protein whose C-terminal domain catalyzes EC 2.7.7.75.
|
| 2.7.7.75 |
Molybdopterin adenylyltransferase.
based on mapping to UniProt Q9NQX3
ATP + molybdopterin = diphosphate + adenylyl-molybdopterin.
-!- Catalyzes the activation of molybdopterin for molybdenum insertion. -!- In eukaryotes, this reaction is catalyzed by the C-terminal domain of a fusion protein that also includes molybdopterin molybdotransferase (EC 2.10.1.1). -!- The reaction requires a divalent cation such as Mg(2+) or Mn(2+). -!- Catalyzes the activation of molybdopterin for molybdenum insertion. -!- In eukaryotes, this reaction is catalyzed by the C-terminal domain of a fusion protein that also includes EC 2.10.1.1. -!- Formerly EC 2.7.7.n5.
|
UniProtKB Entries (1)
| Q9NQX3 |
GEPH_HUMAN
Homo sapiens
Gephyrin
|
PDB Structure
| PDB | 1JLJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structures of human gephyrin and plant Cnx1 G domains: comparative analysis and functional implications.
J.Mol.Biol.
|
