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CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Estrogen sulfotransferase

Enzyme Information

2.8.2.4
Estrone sulfotransferase.
based on mapping to UniProt P49888
3'-phosphoadenylyl sulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate.

UniProtKB Entries (1)

P49888
ST1E1_HUMAN
Homo sapiens
Estrogen sulfotransferase

PDB Structure

PDB 1HY3
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the human estrogen sulfotransferase-PAPS complex: evidence for catalytic role of Ser137 in the sulfuryl transfer reaction.
Pedersen, L.C., Petrotchenko, E., Shevtsov, S., Negishi, M.
J.Biol.Chem.
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