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1 keywords

CATH Domain 1hlpA01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.110 L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2
Homologous Superfamily 3.90.110.10 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal

Domain Context

CATH Clusters

Superfamily Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family

Enzyme Information

1.1.1.37
Malate dehydrogenase.
based on mapping to UniProt Q07841
(S)-malate + NAD(+) = oxaloacetate + NADH.
-!- Also oxidizes some other 2-hydroxydicarboxylic acids.

UniProtKB Entries (1)

Q07841
MDH_HALMA
Haloarcula marismortui ATCC 43049
Malate dehydrogenase

PDB Structure

PDB 1HLP
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural Features That Stabilize Halophilic Malate Dehydrogenase from an Archaebacterium.
Dym, O., Mevarech, M., Sussman, J.L.
Science
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