×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily Glycosidases
Functional Family Mannan endo-1,4-beta-mannosidase

Enzyme Information

3.2.1.78
Mannan endo-1,4-beta-mannosidase.
based on mapping to UniProt P49424
Random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.

UniProtKB Entries (1)

P49424
MANA_CELJU
Cellvibrio japonicus Ueda107
Mannan endo-1,4-beta-mannosidase

PDB Structure

PDB 1GVY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Substrate Distortion by a Beta-Mannanase: Snapshots of the Michaelis and Covalent-Intermediate Complexes Suggest a B2,5 Conformation for the Transition State
Ducros, V., Zechel, D.L., Murshudov, G., Gilbert, H.J., Szabo, L., Stoll, D., Withers, S.G., Davies, G.J.
Angew.Chem.Int.Ed.Engl.
CATH-Gene3D is a Global Biodata Core Resource Learn more...