CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.800 | Arginase; Chain A |
|
3.40.800.10 | Ureohydrolase domain |
Domain Context
CATH Clusters
| Superfamily | Ureohydrolase domain |
| Functional Family |
Enzyme Information
| 3.5.3.22 |
Proclavaminate amidinohydrolase.
based on mapping to UniProt P0DJQ3
Amidinoproclavaminate + H(2)O = proclavaminate + urea.
-!- Forms part of the pathway for the biosythesis of the beta-lactamase inhibitor clavulanate in Streptomyces clavuligerus. -!- It carries out an intermediary reaction between the first reaction of EC 1.14.11.21, and the second and third reactions of that enzyme.
|
UniProtKB Entries (1)
| P0DJQ3 |
PAH_STRCL
Streptomyces clavuligerus
Proclavaminate amidinohydrolase
|
PDB Structure
| PDB | 1GQ6 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Oligomeric Structure of Proclavaminic Acid Amidino Hydrolase: Evolution of a Hydrolytic Enzyme in Clavulanic Acid Biosynthesis
Biochem.J.
|
