CATH Domain 1go4A00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.900	Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A
	3.30.900.10	HORMA domain

Domain Context

CATH Clusters

Superfamily	HORMA domain
Functional Family	Mitotic spindle assembly checkpoint protein MAD2A

Enzyme Information

UniProtKB Entries (1)

MD2L1_HUMAN

Homo sapiens

Mitotic spindle assembly checkpoint protein MAD2A

PDB Structure

PDB	1GO4
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint. Sironi, L., Mapelli, M., Knapp, S., De Antoni, A., Jeang, K.T., Musacchio, A. EMBO J.