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1 keywords

CATH Domain 1f7zI00

CATH Classification

Level CATH Code Description
Class 4 Few Secondary Structures
Architecture 4.10 Irregular
Topology 4.10.410 Factor Xa Inhibitor
Homologous Superfamily 4.10.410.10 Pancreatic trypsin inhibitor Kunitz domain

Domain Context

CATH Clusters

Superfamily Pancreatic trypsin inhibitor Kunitz domain
Functional Family Pancreatic trypsin inhibitor

Enzyme Information

UniProtKB Entries (2)

P00974
BPT1_BOVIN
Bos taurus
Pancreatic trypsin inhibitor
P00763
TRY2_RAT
Rattus norvegicus
Anionic trypsin-2

PDB Structure

PDB 1F7Z
External Links
Method X-RAY DIFFRACTION
Organism Saccharomyces
Primary Citation
The energetic cost of induced fit catalysis: Crystal structures of trypsinogen mutants with enhanced activity and inhibitor affinity.
Pasternak, A., White, A., Jeffery, C.J., Medina, N., Cahoon, M., Ringe, D., Hedstrom, L.
Protein Sci.
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