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1 keywords

CATH Domain 1eziA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.550 Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Homologous Superfamily 3.90.550.10 Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

Domain Context

CATH Clusters

Superfamily Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Functional Family

Enzyme Information

2.7.7.43
N-acylneuraminate cytidylyltransferase.
based on mapping to UniProt P0A0Z8
CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate.
-!- Acts on N-acetyl- and N-glycolyl- derivatives.

UniProtKB Entries (1)

P0A0Z8
NEUA_NEIME
Neisseria meningitidis
N-acylneuraminate cytidylyltransferase

PDB Structure

PDB 1EZI
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of a sialic acid-activating synthetase, CMP-acylneuraminate synthetase in the presence and absence of CDP.
Mosimann, S.C., Gilbert, M., Dombroswki, D., To, R., Wakarchuk, W., Strynadka, N.C.
J.Biol.Chem.
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