CATH Domain 1emsA02

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.428	HIT family, subunit A
	3.30.428.10	HIT-like

Domain Context

CATH Clusters

Superfamily	HIT-like
Functional Family	Fragile histidine triad

Enzyme Information

3.6.1.29	Bis(5'-adenosyl)-triphosphatase. based on mapping to UniProt O76463 P(1)-P(3)-bis(5'-adenosyl) triphosphate + H(2)O = ADP + AMP.
3.5.-.-	Acting on carbon-nitrogen bonds, other than peptide bonds. based on mapping to UniProt O76463

UniProtKB Entries (1)

NFT1_CAEEL

Caenorhabditis elegans

Nitrilase and fragile histidine triad fusion protein NitFhit

PDB Structure

PDB	1EMS
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal structure of the worm NitFhit Rosetta Stone protein reveals a Nit tetramer binding two Fhit dimers. Pace, H.C., Hodawadekar, S.C., Draganescu, A., Huang, J., Bieganowski, P., Pekarsky, Y., Croce, C.M., Brenner, C. Curr.Biol.