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1 keywords

CATH Domain 1ejfB00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.790  

Domain Context

CATH Clusters

Superfamily 2.60.40.790
Functional Family prostaglandin E synthase 3

Enzyme Information

5.3.99.3
Prostaglandin-E synthase.
based on mapping to UniProt Q15185
(5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate.
-!- Brings about the opening of the epidioxy bridge.

UniProtKB Entries (1)

Q15185
TEBP_HUMAN
Homo sapiens
Prostaglandin E synthase 3

PDB Structure

PDB 1EJF
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure and activity of human p23, a heat shock protein 90 co-chaperone.
Weaver, A.J., Sullivan, W.P., Felts, S.J., Owen, B.A., Toft, D.O.
J.Biol.Chem.
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