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CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.91.20
Functional Family

Enzyme Information

3.1.21.4
Type II site-specific deoxyribonuclease.
based on mapping to UniProt Q45488
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
-!- Large group of enzymes which recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition site. -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/

UniProtKB Entries (1)

Q45488
T2B2_BACIU
Bacillus subtilis
Type-2 restriction enzyme BglII

PDB Structure

PDB 1DFM
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Understanding the immutability of restriction enzymes: crystal structure of BglII and its DNA substrate at 1.5 A resolution.
Lukacs, C.M., Kucera, R., Schildkraut, I., Aggarwal, A.K.
Nat.Struct.Biol.
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