CATH Domain 1dbrB00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.2020

Domain Context

CATH Clusters

Superfamily	3.40.50.2020
Functional Family

Enzyme Information

2.4.2.8	Hypoxanthine phosphoribosyltransferase. based on mapping to UniProt Q26997 IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate. -!- Guanine and 6-mercaptopurine can replace hypoxanthine.
2.4.2.22	Xanthine phosphoribosyltransferase. based on mapping to UniProt Q26997 XMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine.

UniProtKB Entries (1)

HGXR_TOXGO

Toxoplasma gondii

Hypoxanthine-guanine-xanthine phosphoribosyltransferase

PDB Structure

PDB	1DBR
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal structures of Toxoplasma gondii HGXPRTase reveal the catalytic role of a long flexible loop. Schumacher, M.A., Carter, D., Ross, D.S., Ullman, B., Brennan, R.G. Nat.Struct.Biol.