CATH Domain 1cm2A00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.1340	Histidine-containing Protein; Chain: A;
	3.30.1340.10	HPr-like

Domain Context

CATH Clusters

Superfamily	HPr-like
Functional Family	Phosphocarrier, HPr family

Enzyme Information

UniProtKB Entries (1)

PTHP_ECOLI

Escherichia coli K-12

Phosphocarrier protein HPr

PDB Structure

PDB	1CM2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	The aspartyl replacement of the active site histidine in histidine-containing protein, HPr, of the Escherichia coli Phosphoenolpyruvate:Sugar phosphotransferase system can accept and donate a phosphoryl group. Spontaneous dephosphorylation of acyl-phosphate autocatalyzes an internal cyclization Napper, S., Delbaere, L.T., Waygood, E.B. J.Biol.Chem.