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CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Complement factor D

Enzyme Information

3.4.21.20
Cathepsin G.
based on mapping to UniProt P08311
Specificity similar to chymotrypsin C.
-!- From azurophil granules of polymorphonuclear leukocytes. -!- Belongs to peptidase family S1.

UniProtKB Entries (1)

P08311
CATG_HUMAN
Homo sapiens
Cathepsin G

PDB Structure

PDB 1CGH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: a Janus-faced proteinase with two opposite specificities.
Hof, P., Mayr, I., Huber, R., Korzus, E., Potempa, J., Travis, J., Powers, J.C., Bode, W.
EMBO J.
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