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1 keywords

CATH Domain 1aokB00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.20 Up-down Bundle
Topology 1.20.90 Phospholipase A2
Homologous Superfamily 1.20.90.10 Phospholipase A2 domain

Domain Context

CATH Clusters

Superfamily Phospholipase A2 domain
Functional Family Basic phospholipase A2 homolog

Enzyme Information

3.1.1.4
Phospholipase A(2).
based on mapping to UniProt P14420
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.

UniProtKB Entries (1)

P04084
PA2A_VIPAE
Vipera ammodytes meridionalis
Acidic phospholipase A2 homolog vipoxin A chain

PDB Structure

PDB 1AOK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of vipoxin at 2.0 A: an example of regulation of a toxic function generated by molecular evolution.
Perbandt, M., Wilson, J.C., Eschenburg, S., Mancheva, I., Aleksiev, B., Genov, N., Willingmann, P., Weber, W., Singh, T.P., Betzel, C.
FEBS Lett.
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