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CATH Classification

Domain Context

CATH Clusters

Superfamily P1 Nuclease
Functional Family Phospholipase C

Enzyme Information

3.1.4.3
Phospholipase C.
based on mapping to UniProt P09598
A phosphatidylcholine + H(2)O = 1,2-diacyl-sn-glycerol + phosphocholine.
-!- The bacterial enzyme also acts on sphingomyelin and phosphatidylinositol. -!- The enzyme from seminal plasma does not act on phosphatidylinositol.

UniProtKB Entries (1)

P09598
PHLC_BACCE
Bacillus cereus
Phospholipase C

PDB Structure

PDB 1AH7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
High-resolution (1.5 A) crystal structure of phospholipase C from Bacillus cereus.
Hough, E., Hansen, L.K., Birknes, B., Jynge, K., Hansen, S., Hordvik, A., Little, C., Dodson, E., Derewenda, Z.
Nature
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