The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Zinc finger, CCHC-type
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 159: Terminal uridylyl transferase 4

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 B2RX14 (/IPI)
MiRNA binding GO:0035198
Interacting selectively and non-covalently with a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes.
1 B2RX14 (/IDA)
RNA uridylyltransferase activity GO:0050265
Catalysis of the reaction: UTP + RNA(n) = diphosphate + RNA(n+1).
1 B2RX14 (/IDA)
RNA uridylyltransferase activity GO:0050265
Catalysis of the reaction: UTP + RNA(n) = diphosphate + RNA(n+1).
1 B2RX14 (/ISO)
Uridylyltransferase activity GO:0070569
Catalysis of the transfer of an uridylyl group to an acceptor.
1 B2RX14 (/IDA)
Uridylyltransferase activity GO:0070569
Catalysis of the transfer of an uridylyl group to an acceptor.
1 B2RX14 (/IMP)

There are 22 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Oocyte maturation GO:0001556
A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.
1 B2RX14 (/IMP)
Cytokine production GO:0001816
The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
1 B2RX14 (/IDA)
Negative regulation of transposition, RNA-mediated GO:0010526
Any process that decreases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.
1 B2RX14 (/ISO)
Negative regulation of transposition, RNA-mediated GO:0010526
Any process that decreases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.
1 B2RX14 (/ISS)
MiRNA metabolic process GO:0010586
The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.
1 B2RX14 (/IMP)
MiRNA metabolic process GO:0010586
The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.
1 B2RX14 (/ISO)
MiRNA metabolic process GO:0010586
The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.
1 B2RX14 (/ISS)
MiRNA catabolic process GO:0010587
The chemical reactions and pathways resulting in the breakdown of miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.
1 B2RX14 (/ISO)
MiRNA catabolic process GO:0010587
The chemical reactions and pathways resulting in the breakdown of miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.
1 B2RX14 (/ISS)
Stem cell population maintenance GO:0019827
The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
1 B2RX14 (/ISO)
Stem cell population maintenance GO:0019827
The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
1 B2RX14 (/ISS)
Pre-miRNA processing GO:0031054
Any process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule.
1 B2RX14 (/ISO)
Pre-miRNA processing GO:0031054
Any process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule.
1 B2RX14 (/ISS)
RNA 3'-end processing GO:0031123
Any process involved in forming the mature 3' end of an RNA molecule.
1 B2RX14 (/IDA)
RNA 3'-end processing GO:0031123
Any process involved in forming the mature 3' end of an RNA molecule.
1 B2RX14 (/ISO)
Regulation of lipopolysaccharide-mediated signaling pathway GO:0031664
Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
1 B2RX14 (/IDA)
Negative regulation of NF-kappaB transcription factor activity GO:0032088
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.
1 B2RX14 (/IDA)
Positive regulation of interleukin-6 production GO:0032755
Any process that activates or increases the frequency, rate, or extent of interleukin-6 production.
1 B2RX14 (/IMP)
Interleukin-6-mediated signaling pathway GO:0070102
A series of molecular signals initiated by the binding of interleukin-6 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 B2RX14 (/IMP)
RNA 3' uridylation GO:0071076
The enzymatic addition of a sequence of uridylyl residues at the 3' end of an RNA molecule.
1 B2RX14 (/IDA)
RNA 3' uridylation GO:0071076
The enzymatic addition of a sequence of uridylyl residues at the 3' end of an RNA molecule.
1 B2RX14 (/IMP)
Polyuridylation-dependent mRNA catabolic process GO:1990074
The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end of the target mRNA.
1 B2RX14 (/IMP)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 B2RX14 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 B2RX14 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 B2RX14 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 B2RX14 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 B2RX14 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 B2RX14 (/ISO)
Cytoplasmic ribonucleoprotein granule GO:0036464
A ribonucleoprotein granule located in the cytoplasm.
1 B2RX14 (/ISO)
Cytoplasmic ribonucleoprotein granule GO:0036464
A ribonucleoprotein granule located in the cytoplasm.
1 B2RX14 (/ISS)