The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aspartate Aminotransferase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 56: Kynureninase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Kynureninase activity GO:0030429
Catalysis of the reaction: L-kynurenine + H2O = anthranilate + L-alanine.
2 P70712 (/IDA) Q16719 (/IDA)
3-hydroxykynureninase activity GO:0061981
Catalysis of the reaction: L-3-hydroxykynurenine + H2O = 3-hydroxyanthranilate + L-alanine.
2 P70712 (/ISS) Q9CXF0 (/ISS)
Pyridoxal phosphate binding GO:0030170
Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
1 P70712 (/IDA)
Pyridoxal phosphate binding GO:0030170
Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
1 Q9CXF0 (/ISO)
Kynureninase activity GO:0030429
Catalysis of the reaction: L-kynurenine + H2O = anthranilate + L-alanine.
1 Q16719 (/IMP)
Kynureninase activity GO:0030429
Catalysis of the reaction: L-kynurenine + H2O = anthranilate + L-alanine.
1 Q9CXF0 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q16719 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q9CXF0 (/ISO)
3-hydroxykynureninase activity GO:0061981
Catalysis of the reaction: L-3-hydroxykynurenine + H2O = 3-hydroxyanthranilate + L-alanine.
1 Q16719 (/IDA)
3-hydroxykynureninase activity GO:0061981
Catalysis of the reaction: L-3-hydroxykynurenine + H2O = 3-hydroxyanthranilate + L-alanine.
1 Q9CXF0 (/ISO)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
NAD biosynthetic process GO:0009435
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
2 P70712 (/ISS) Q9CXF0 (/ISS)
Tryptophan catabolic process GO:0006569
The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
1 Q16719 (/IMP)
Tryptophan catabolic process GO:0006569
The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
1 Q9CXF0 (/ISO)
Tryptophan catabolic process GO:0006569
The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
1 Q16719 (/TAS)
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
1 P70712 (/IEP)
NAD biosynthetic process GO:0009435
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
1 Q16719 (/IMP)
NAD biosynthetic process GO:0009435
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
1 Q9CXF0 (/ISO)
Tryptophan catabolic process to acetyl-CoA GO:0019442
The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including acetyl-CoA.
1 P70712 (/IDA)
Tryptophan catabolic process to acetyl-CoA GO:0019442
The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including acetyl-CoA.
1 Q9CXF0 (/ISO)
Quinolinate biosynthetic process GO:0019805
The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.
1 Q16719 (/IDA)
Quinolinate biosynthetic process GO:0019805
The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.
1 Q9CXF0 (/ISO)
Response to interferon-gamma GO:0034341
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon.
1 Q16719 (/IDA)
Response to interferon-gamma GO:0034341
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon.
1 Q9CXF0 (/ISO)
Response to vitamin B6 GO:0034516
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.
1 Q16719 (/IMP)
Response to vitamin B6 GO:0034516
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.
1 Q9CXF0 (/ISO)
Anthranilate metabolic process GO:0043420
The chemical reactions and pathways involving anthranilate (2-aminobenzoate).
1 Q16719 (/IDA)
Anthranilate metabolic process GO:0043420
The chemical reactions and pathways involving anthranilate (2-aminobenzoate).
1 Q9CXF0 (/ISO)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P70712 (/IDA) Q16719 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q16719 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q9CXF0 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9CXF0 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q16719 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9CXF0 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9CXF0 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q16719 (/TAS)