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CATH Superfamily 3.90.110.10

Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: L-lactate dehydrogenase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
L-lactate dehydrogenase activity GO:0004459
Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+.
 111 Q81K80 (/ISS) Q81K80 (/ISS) Q81K80 (/ISS) Q81K80 (/ISS) Q81K80 (/ISS) Q81K80 (/ISS) Q81K80 (/ISS) Q81K80 (/ISS) Q81K80 (/ISS) Q81K80 (/ISS)
(101 more)
L-lactate dehydrogenase activity GO:0004459
Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+.
 2 P00344 (/IDA) P00344 (/IDA)
NAD binding GO:0051287
Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
 2 P00344 (/IDA) P00344 (/IDA)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
 52 Q81RW4 (/ISS) Q81RW4 (/ISS) Q81RW4 (/ISS) Q81RW4 (/ISS) Q81RW4 (/ISS) Q81RW4 (/ISS) Q81RW4 (/ISS) Q81RW4 (/ISS) Q81RW4 (/ISS) Q81RW4 (/ISS)
(42 more)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.