The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
(Glycosyl)asparaginase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Isoaspartyl peptidase/L-asparaginase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Asparaginase activity GO:0004067
Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3.
16 Q32LE5 (/ISS) Q4R7U8 (/ISS) Q4R7U8 (/ISS) Q4R7U8 (/ISS) Q4R7U8 (/ISS) Q5BKW9 (/ISS) Q5BKW9 (/ISS) Q6GM78 (/ISS) Q8C0M9 (/ISS) Q8EF71 (/ISS)
(6 more)
Beta-aspartyl-peptidase activity GO:0008798
Catalysis of the cleavage of a beta-linked aspartic residue from the N-terminus of a polypeptide.
10 Q32LE5 (/ISS) Q4R7U8 (/ISS) Q4R7U8 (/ISS) Q4R7U8 (/ISS) Q4R7U8 (/ISS) Q5BKW9 (/ISS) Q5BKW9 (/ISS) Q6GM78 (/ISS) Q8C0M9 (/ISS) Q8VI04 (/ISS)
Asparaginase activity GO:0004067
Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3.
9 P37595 (/IDA) P37595 (/IDA) P50287 (/IDA) Q7L266 (/IDA) Q7L266 (/IDA) Q8GXG1 (/IDA) Q8GXG1 (/IDA) Q8GXG1 (/IDA) Q8VI04 (/IDA)
Beta-aspartyl-peptidase activity GO:0008798
Catalysis of the cleavage of a beta-linked aspartic residue from the N-terminus of a polypeptide.
4 P37595 (/IDA) P37595 (/IDA) Q7L266 (/IDA) Q7L266 (/IDA)
Asparaginase activity GO:0004067
Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3.
2 Q7L266 (/IMP) Q7L266 (/IMP)
Hydrolase activity GO:0016787
Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
2 P37595 (/IDA) P37595 (/IDA)
Asparaginase activity GO:0004067
Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3.
1 Q8C0M9 (/ISO)
Beta-aspartyl-peptidase activity GO:0008798
Catalysis of the cleavage of a beta-linked aspartic residue from the N-terminus of a polypeptide.
1 Q8C0M9 (/ISO)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Asparagine catabolic process via L-aspartate GO:0033345
The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-aspartate.
14 Q29I93 (/ISS) Q32LE5 (/ISS) Q4R7U8 (/ISS) Q4R7U8 (/ISS) Q4R7U8 (/ISS) Q4R7U8 (/ISS) Q5BKW9 (/ISS) Q5BKW9 (/ISS) Q6GM78 (/ISS) Q7L266 (/ISS)
(4 more)
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
7 Q8EF71 (/ISS) Q9KNX7 (/ISS) Q9KNX7 (/ISS) Q9KNX7 (/ISS) Q9KNX7 (/ISS) Q9KNX7 (/ISS) Q9KNX7 (/ISS)
Asparagine catabolic process via L-aspartate GO:0033345
The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-aspartate.
3 Q7L266 (/IDA) Q7L266 (/IDA) Q8VI04 (/IDA)
L-phenylalanine catabolic process GO:0006559
The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpropanoic acid.
2 Q7L266 (/TAS) Q7L266 (/TAS)
Protein autoprocessing GO:0016540
Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein.
2 P37595 (/IMP) P37595 (/IMP)
Asparagine catabolic process via L-aspartate GO:0033345
The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-aspartate.
1 Q8C0M9 (/ISO)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
14 Q29I93 (/ISS) Q32LE5 (/ISS) Q4R7U8 (/ISS) Q4R7U8 (/ISS) Q4R7U8 (/ISS) Q4R7U8 (/ISS) Q5BKW9 (/ISS) Q5BKW9 (/ISS) Q6GM78 (/ISS) Q7L266 (/ISS)
(4 more)
Photoreceptor inner segment GO:0001917
The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
11 Q32LE5 (/ISS) Q4R7U8 (/ISS) Q4R7U8 (/ISS) Q4R7U8 (/ISS) Q4R7U8 (/ISS) Q5BKW9 (/ISS) Q5BKW9 (/ISS) Q6GM78 (/ISS) Q7L266 (/ISS) Q7L266 (/ISS)
(1 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q7L266 (/IDA) Q7L266 (/IDA) Q8VI04 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q7L266 (/HDA) Q7L266 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q7L266 (/TAS) Q7L266 (/TAS)
Photoreceptor inner segment GO:0001917
The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
1 Q8C0M9 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8C0M9 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P50287 (/IDA)