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CATH Superfamily 3.50.50.60

FAD/NAD(P)-binding domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
FAD/NAD(P)-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 398: p-hydroxybenzoate hydroxylase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
4-hydroxybenzoate 3-monooxygenase. [EC: 1.14.13.2]
4-hydroxybenzoate + NADPH + O(2) = protocatechuate + NADP(+) + H(2)O.
  • Most enzymes from Pseudomonas are highly specific for NAD(P)H (cf. EC 1.14.13.33).
 20 A0A233TK29 A0A233TK29 A0A233TK29 A0A233TK29 A0A367MFY2 A0A367MFY2 P00438 P00438 P00438 P00438
(10 more...)
4-hydroxybenzoate 3-monooxygenase (NAD(P)H). [EC: 1.14.13.33]
4-hydroxybenzoate + NAD(P)H + O(2) = 3,4-dihydroxybenzoate + NAD(P)(+) + H(2)O.
  • The enzyme from Corynebacterium cyclohexanicum is highly specific for 4-hydroxybenzoate, but uses NADH and NADPH at approximately equal rates (cf. EC 1.14.13.2).
  • It is less specific for NADPH than EC 1.14.13.2.
 1 C4TP09