The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
FAD/NAD(P)-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17: Fumarate reductase flavoprotein subunit

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Succinate dehydrogenase activity GO:0000104
Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor.
106 P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA)
(96 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
106 P00363 (/IPI) P00363 (/IPI) P00363 (/IPI) P00363 (/IPI) P00363 (/IPI) P00363 (/IPI) P00363 (/IPI) P00363 (/IPI) P00363 (/IPI) P00363 (/IPI)
(96 more)
Electron transfer activity GO:0009055
Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
106 P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA)
(96 more)
FAD binding GO:0071949
Interacting selectively and non-covalently with the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
106 P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA)
(96 more)
FAD binding GO:0071949
Interacting selectively and non-covalently with the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
106 P00363 (/ISM) P00363 (/ISM) P00363 (/ISM) P00363 (/ISM) P00363 (/ISM) P00363 (/ISM) P00363 (/ISM) P00363 (/ISM) P00363 (/ISM) P00363 (/ISM)
(96 more)
Succinate dehydrogenase activity GO:0000104
Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor.
7 Q9KNS5 (/ISS) Q9KNS5 (/ISS) Q9KNS5 (/ISS) Q9KNS5 (/ISS) Q9KNS5 (/ISS) Q9KNS5 (/ISS) Q9KNS5 (/ISS)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fermentation GO:0006113
The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP).
106 P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP)
(96 more)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
106 P00363 (/IEP) P00363 (/IEP) P00363 (/IEP) P00363 (/IEP) P00363 (/IEP) P00363 (/IEP) P00363 (/IEP) P00363 (/IEP) P00363 (/IEP) P00363 (/IEP)
(96 more)
Anaerobic respiration GO:0009061
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor.
106 P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP)
(96 more)
Bacterial-type flagellum assembly GO:0044780
The assembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility.
106 P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP)
(96 more)
Bacterial-type flagellum-dependent cell motility GO:0071973
Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.
106 P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP) P00363 (/IMP)
(96 more)
Anaerobic respiration GO:0009061
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor.
7 Q9KNS5 (/ISS) Q9KNS5 (/ISS) Q9KNS5 (/ISS) Q9KNS5 (/ISS) Q9KNS5 (/ISS) Q9KNS5 (/ISS) Q9KNS5 (/ISS)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
106 P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA)
(96 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
106 P00363 (/HDA) P00363 (/HDA) P00363 (/HDA) P00363 (/HDA) P00363 (/HDA) P00363 (/HDA) P00363 (/HDA) P00363 (/HDA) P00363 (/HDA) P00363 (/HDA)
(96 more)
Plasma membrane fumarate reductase complex GO:0045284
A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR00224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. In some species, the complex has only three subunits, and in these cases, there is only one membrane anchor instead of two. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)). Examples of this component are found in bacterial species.
106 P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA) P00363 (/IDA)
(96 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
10 P9WN91 (/HDA) P9WN91 (/HDA) P9WN91 (/HDA) P9WN91 (/HDA) P9WN91 (/HDA) P9WN91 (/HDA) P9WN91 (/HDA) P9WN91 (/HDA) P9WN91 (/HDA) P9WN91 (/HDA)